Cannabinoid Type 2 and Autism

Researchers in Naples have found some differences in the average autistic child’s endocannabinoid system. Having more CB2 receptors (Both Cannabidiol and THC bind to this receptor), may explain why many autistic people find cannabis useful, and also why it doesn’t seem to matter too much whether it’s THC or CBD or both in many cases. More research is needed.


Cannabinoid Receptor Type 2, but not Type 1, is Up-Regulated in Peripheral Blood Mononuclear Cells of Children Affected by Autistic Disorders.

Division of Pharmacology, Department of Experimental Medicine, Second University of Naples, via S. Maria di Costantinopoli, 16, 80138, Naples, Italy,


Autistic disorders (ADs) are heterogeneous neurodevelopmental disorders arised by the interaction of genes and environmental factors. Dysfunctions in social interaction and communication skills, repetitive and stereotypic verbal and non-verbal behaviours are common features of ADs.

There are no defined mechanisms of pathogenesis, rendering curative therapy very difficult. Indeed, the treatments for autism presently available can be divided into behavioural, nutritional and medical approaches, although no defined standard approach exists.

Autistic children display immune system dysregulation and show an altered immune response of peripheral blood mononuclear cells (PBMCs).

In this study, we investigated the involvement of cannabinoid system in PBMCs from autistic children compared to age-matched normal…

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About cannabisforautism

An Ashtanga Yoga teacher, dedicated to improving the health and welfare of those involved in mental health issues, substance use or homelessness. I am also striving to put an end to the perception of the substance user as someone who makes incorrect choices. Striving for a world where there are no 'drug abusers' or 'addicts', just substance users with health concerns and sometimes financial and legal confounds. It is possible to use many substances and still remain happier and healthier than your peers. The notion that a substance user must become unhealthier as time goes by is false. I hope you enjoy reading my blog. It's about autism treatments and a few other odds and ends. Thank you and take care, Jules
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5 Responses to Cannabinoid Type 2 and Autism

  1. Anthony says:

    Hi my son is six and diagnosed PDD nos and we r thinking of trying hemp oil and are looking for some direction if anyone could please help

    • Hi Anthony, ‘Hemp Oil’ comes from the pressed seeds of the cannabis plant – it’s very healthy, you should use it if you can afford it, for cooking, but it’s not the medicine!
      The medicine is ‘cannabis oil’ or ‘cannabis flower oil’ – obtained from the flowers not the seeds. For the oil, you are pretty much on your own. Experiment! Start with a small amount to be safer and taste it yourself before giving it to your child so you can know how it is feeling for him. Every ‘cannabis oil’ is different and may have different effects!

      • jason webb says:

        i live in northern california and can put you in touch with the correct doctors immediately..
        best Regards,

  2. If youre remodel bathroom costing your kitchen?
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    Remember, remodel bathroom costing your kitchen on a budget and
    this is partly due to the wide range of wood finishes from maple and pine to oak and cherry.
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    • That’s very kind of you. I usually wouldn’t approve a comment of this nature but since it’s rather inoffensive and the kitchen is the social heart of the home, I do approve.
      Take care and best of luck with your enterprise! x

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