Use of dronabinol (delta-9-THC) in autism

A prospective single-case-study with an early infantile autistic child.

René Kurz, Kurt Blaas. 21 Nov 2010


Objective: To evaluate the effectiveness of dronabinol (delta-9-THC) as supplementary therapy in a child with autistic disorder.

Methods: A child who met the DSM-IV (Diagnostic and Statistical Manual of Mental Disorders) criteria for a diagnosis of autistic disorder and who took no other medication during the observation time was included in an open and uncontrolled study. Symptom assessment was performed using the Aberrant Behavior Checklist (ABC) before and after six months of medical treatment.

Result: Compared to baseline, significant improvements were observed for hyperactivity, lethargy, irritability, stereotypy and inappropriate speech at follow-up (p=0.043).

Conclusion: This study showed that the use of dronabinol may be able to reduce the symptoms of autism.

Keywords: early infantile autism, autistic disorder, dronabinol, cannabinoid

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Or read an article about it here.


About cannabisforautism

An Ashtanga Yoga teacher, dedicated to improving the health and welfare of those involved in mental health issues, substance use or homelessness. I am also striving to put an end to the perception of the substance user as someone who makes incorrect choices. Striving for a world where there are no 'drug abusers' or 'addicts', just substance users with health concerns and sometimes financial and legal confounds. It is possible to use many substances and still remain happier and healthier than your peers. The notion that a substance user must become unhealthier as time goes by is false. I hope you enjoy reading my blog. It's about autism treatments and a few other odds and ends. Thank you and take care, Jules
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2 Responses to Use of dronabinol (delta-9-THC) in autism

  1. Reblogged this on An Autism State Of Mind and commented:
    Very interesting..

  2. I’m not a big fan of Dronabinol (Marinol). And while I’m sure I’m preaching to the choir here… I’ll still take this chance to remind people to write. call. or even better yet visit their local, state, and federal legislators. Until cannabis is rescheduled- and the NIH/NIDA/DEA strangehold on cannabis for medical research changes…we will see few improvements.
    State medical marijuana laws are a great thing. But until we can have open research using cannabis. Get real data. Be able to isolate various constiutents of the cannabis species and find the most effective delivery methods for various conditions…we will continue to see much unneeded suffering.

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